Synthesis, Mechanistic Interpretation and Kinetic Study of 2,6 Di-methylphenyl Phosphate Monoester in Acid Medium

Extensive kinetic study has been carried out on the hydrolysis of mono-2,6-dimethylphenyl phosphate ester in acid 0.1 to 6.0 mol. dm.HCl and buffers from 1.24 to 7.46 pH at 97± 0.5°C in water. Systematic ionic data proves the presence of acid catalyzed hydrolysis. The monoester has been found to be hydrolysis by conjugate acid, mono-negative, neutral and di -negative species. The inorganic phosphate obtained in overall hydrolysis has been estimated by Allen’s modified method. Study of the reaction and dioxanewater mixture suggested the nature of transition state in which charges are developed due to bimolecular attack of water molecule. Comparative isokinetic rate data of similarly substituted other phosphate monoesters, whose mechanism is known, supported P-O bond fission.